Nature, Published online: 25 February 2026; doi:10.1038/s41586-026-10127-0
Although the pouches are considered a tobacco product, they don’t contain any tobacco, and are instead made from the plant fiber cellulose. There’s a blend of nicotine powder in the pouch, which is then mixed with sweeteners and flavoring. Because the pouch is placed between one’s gums and cheek, the nicotine enters the bloodstream directly, no smoking or spitting needed.
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