CRISPR–Cas9 screening identifies CLCC1 as a factor that increases neutral lipid flux to prevent hepatic steatosis and promotes nuclear pore complex assembly by promoting membrane bending and fusion.
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A few years later, in 2024, researchers in multiple labs were horrified to notice toxic batches of agar for reasons as yet unclear. After they observed a worrying lack of microbial growth (impeding their ability to carry out basic experiments), they switched to different agar suppliers, and their results improved.
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